News

1. 1. Assistant Professor Tian Chong has been awarded with the 2023 Organic Chemistry Horizon Prize: Perkin Prize in Physical Organic Chemistry. This prestigious recognition comes as part of the distinguished team of researchers known as the “Molecular Ratcheteers” from around the world. The team, consisting of 20 researchers, was awarded for their groundbreaking work in catalyzed non-equilibrium systems, with a specific focus on molecular ratchet mechanisms. https://www.science.nus.edu.sg/blog/2023/07/24/organic-chemistry-horizon-prize-perkin-prize-in-physical-organic-chemistry-2023/

She has also been awarded the NMRC- New Investigator Grant (NIG) for her work in biocompatible/biomimetic molecular machines and mechanically interlocked molecules. These cutting-edge areas hold promising potential in performing sophisticated tasks within biological systems and addressing challenging questions related to drug discovery and delivery.

• 2. Assist Prof Liu Boxiang has received a MOE Tier 2 grant in which he proposed to identify cell-type-specific target risk genes for type-2 diabetes (T2D) in adipose tissues from East Asian populations: The incidence of T2D in Singapore is the highest among developed countries, yet donors of Asian descent are severely underrepresented in genetic studies of T2D. The team aims to characterize the Asian-specific genetic architecture of adipose tissues to unravel the molecular mechanisms of T2D susceptibility.

1. 3. Assist Prof Gloryn Chia has received a MOE Tier 2 grant in which she will attempt to decipher the neoantigen landscape and T cell recognition in colorectal cancer: To develop effective immunotherapies, it is crucial to comprehend the mechanisms that result in the lack of T cell response. The team’s objective is to empirically analyze the recognition of neoantigens by T cells and identify the mechanisms that lead to their dysfunctional state. This will enable the development of more effective immunotherapy for treating colorectal cancer.
   4. Assist Prof Tang Wei has received a MOE Tier 2 grant which is aimed at to develop pulmonary circular mRNA Nanovaccines: Mucosal surfaces are the primary site of entry for viruses into the body. There is a critical need for vaccines that induce potent and durable immunity while efficiently targeting mucosal sites. The team’s objective is to develop a new vaccine technology by leveraging lipid nanoparticles for the pulmonary delivery of circular RNA and to study their immunomodulation mechanisms and immunoprophylaxis against respiratory infections.
   5. Ms Yong Sock Leng was awarded National Day Awards 2023 Efficiency Medal.