BSc Chemistry, University of Science and Technology of China, China PhD Chemistry, University of Georgia, USA Postdoctoral fellow, National Institutes of Health, USA
Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore 18 Science Drive 4, Singapore 117543 Office: S9 15-01D Tel: +65 6601 6515 Fax: +65 6779 1554 Email: wei.tang@nus.edu.sg Website: www.tangweilab.com
Research Interests:
Our research group aims to develop safe and effective drug delivery technologies to empower early detection, precise stratification, and personalized therapy for cancer and other human healthcare challenges. To accomplish this goal, we integrate chemistry, biomaterials science, nanomedicine, molecular imaging, and immunoengineering fundamentals to study the relationship between in vivo drug transport and biological barriers to the drug delivery systems. Specifically, the group is interested in designing advanced delivery systems in the following applications.
Precision nanomedicine
We synthesize smart nanoparticles to pack imaging probes, chemotherapeutics, nucleic acids (mRNA, siRNA, miRNA), and/or immunomodulators and to target physiological characteristics, stroma cells, and/or metabolic interactions in the tumor microenvironment for precision nanomedicine.
Engineering immunotherapy
We develop innovative biomaterial-inspired strategies to modulate the crosstalk between cancer cells and immune cells in the cancer immunity cycle for effective vaccine delivery and immunotherapy.
Translational delivery
We implement multidisciplinary approaches to enhance in vivo transport of diagnostics and therapeutics across biological barriers such as the respiratory mucosa, the small intestine, and skin.