A/Prof CHEW Eng Hui

A/Prof CHEW Eng Hui

Associate Professor CHEW Eng Hui

  • BSc (Pharm) Hons, National University of Singapore, Singapore
  • PhD (Pharm), University of Nottingham, United Kingdom
  • Registered pharmacist, Singapore Pharmacy Council
  • Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore
  • 18 Science Drive 4, Singapore 117543
  • Tel: +65 6516 1995
  • Fax: +65 6779 1554
  • Email: phaceh@nus.edu.sg

Teaching Activities in NUS

Undergraduate:
Bachelor of Pharmacy (Honours)

  • PR1152 Pharmacy Foundations: Science & Therapeutics I
  • PR3152 Immune and Endocrine Systems: Science & Therapeutics

Bachelor of Science (Pharmaceutical Science) (Honours)

  • PHS2102 Physicochemical and Biochemical Principles of Drug Action

Postgraduate:

  • PR5220 Bioprocess Technology

 

Drug discovery

  • Elucidation of mechanism/s of action of natural products, synthetic and semi-synthetic compounds
  • Characterization and development of agents that possess potential anticancer, chemopreventive, neuroprotective and anti-inflammatory properties

Complementary and Alternative Medicine and Healthcare education

  • Provision of evidence-based information of CAMs to healthcare professionals and trainees via digital means
  • Chairperson (Jan 2023 to present), Continuing Professional Education (CPE) Accreditation Committee, Singapore Pharmacy Council
  • Council member (Apr 2013 to Mar 2015), Pharmaceutical Society of Singapore (PSS)
  • Goh A, Budijono B, Lim C, Chew EH, Yap K. An In-House Developed Probiotics Database E-Reference Information for Healthcare Professionals. Stud Health Technol Inform (2024) 310:239-243.
  • Goh ADY, Ng CSM, Toh YG, Chong JBK, Chew EH, Yap KY. Development of a Probiotics Practice E-Reference Database for Health Care Professionals. Clin Ther (2021) 43(12):e364-e376.
  • Tan SH, Karuppasamy M, Lan P, Zhang Y, Hu J, Lai X, Siok-Cheng Lim B, Liu W, Chen J, Chew EH, Banwell MG. Ribisins and Certain Analogues Exert Neuroprotective Effects through Activation of the Keap1-Nrf2-ARE Pathway. ChemMedChem (2022) 17(18):e202200292.
  • Gan FF, Zhang R, Ng HL, Karuppasamy M, Seah W, Yeap WH, Ong SM, Hadadi E, Wong SC, Chui WK, Chew EH. Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway. Food Chem Toxicol (2018) 116:238-248.
  • Ng HL, Chen S, Chew EH, Chui WK. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity. Eur J Med Chem (2016) 115:63-74.
  • Kaminska KK, Bertrand HC, Tajjima H, Stafford WC, Cheng Q, Chen W, Wells G, Arner ES, Chew EH*. Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads. Oncotarget (2016) 7:40233-40251.
  • Shelar SB, Kaminska KK, Reddy SA, Kumar D, Tan CT, Yu VC, Lu J, Holmgren A, Hagen T, Chew EH. Thioredoxin-dependent regulation of AIF-mediated DNA damage. Free Radic Biol Med (2015) 87:125-136.