Last updated on 29 August 2023
2023
Venkatesan, G., Dancik, Y., Koh, N., Bigliardi, P., & Pastorin, G. (n.d.). Small Molecule Para-Phenylenediamine Analogues with Enhanced Oxidation Potential as Viable Permanent Hair Dyes. ACS Sustainable Chemistry & Engineering, 2023, 11 (33), pp. 12355-12365.
Chong, S.Y., Wang, X., van Bloois, L., Huang, C., Syeda, N.S., Zhang, S., Ting, H.J., Nair, V., Lin, Y., Lou, C.K.L., Benetti, A.A., Yu, X., Lim, N.J.Y., Tan, M.S., Lim, H.Y., Lim, S.Y., Thiam, C.H., Looi, W.D., Zharkova, O., Chew, N.W.S., Ng, C.H., Bonney, G.K., Muthiah, M., Chen, X., Pastorin, G., Richards, A.M., Angeli, V., Storm, G., Wang, J.-W. Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability. Journal of Controlled Release, 2023, 360, pp. 344-364.
Pastorin, G., Benetti, C., Wacker, M.G. From in vitro to in vivo: A comprehensive guide to IVIVC development for long-acting therapeutics. Advanced Drug Delivery Reviews, 2023, 199, art. no. 114906.
Neupane, Y.R., Handral, H.K., Alkaff, S.A., Chng, W.H., Venkatesan, G., Huang, C., Lee, C.K., Wang, J.-W., Sriram, G., Dienzo, R.A., Lu, W.F., Ali, Y., Czarny, B., Pastorin, G. Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing. Acta Pharmaceutica Sinica B, 2023, 13 (5), pp. 1887-1902.
Tong, L., Zhang, S., Liu, Q., Huang, C., Hao, H., Tan, M.S., Yu, X., Lou, C.K.L., Huang, R., Zhang, Z., Liu, T., Gong, P., Ng, C.H., Muthiah, M., Pastorin, G., Wacker, M.G., Chen, X., Storm, G., Lee, C.N., Zhang, L., Yi, H., Wang, J.-W. Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis. Science Advances, 2023, 9 (15), art. no. eade5041.
Chng, W.H., Muthuramalingam, R.P.K., Lou, C.K.L., New, S., Neupane, Y.R., Lee, C.K., Altay Benetti, A., Huang, C., Thoniyot, P., Toh, W.S., Wang, J.-W., Pastorin, G. Extracellular Vesicles and Their Mimetics: A Comparative Study of Their Pharmacological Activities and Immunogenicity Profiles. Pharmaceutics, 2023, 15 (4), art. no. 1290.
Jesenko, T., Brezar, S.K., Cemazar, M., Biasin, A., Tierno, D., Scaggiante, B., Grassi, M., Grassi, C., Dapas, B., Truong, N.H., Abrami, M., Zanconati, F., Bonazza, D., Rizzolio, F., Parisi, S., Pastorin, G., Grassi, G. Targeting Non-Coding RNAs for the Development of Novel Hepatocellular Carcinoma Therapeutic Approaches. Pharmaceutics, 2023, 15 (4), art. no. 1249.
Lim, X.C., Huang, C., Yatim, S.M.J.M., Chong, S.Y., Tan, S.H., Yang, X., Heldt, C.L., Pedersen, J., Talanker, M., Modh, H., Wacker, M.G., Pastorin, G., Chan, S.P., Richards, A.M., Charles, C.J., Chan, M.Y., Wang, J.-W. Temporal Changes in Extracellular Vesicle Hemostatic Protein Composition Predict Favourable Left Ventricular Remodeling after Acute Myocardial Infarction. International Journal of Molecular Sciences, 2023, 24 (1), art. no. 327.
2022
Lian, M.Q., Chng, W.H., Liang, J., Yeo, H.Q., Lee, C.K., Belaid, M., Tollemeto, M., Wacker, M.G., Czarny, B., Pastorin, G. Plant-derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications. Journal of Extracellular Vesicles, 2022, 11 (12), art. no. 12283.
Ou, Y.-H., Liang, J., Chng, W.H., Muthuramalingam, R.P.K., Ng, Z.X., Lee, C.K., Neupane, Y.R., Yau, J.N.N., Zhang, S., Lou, C.K.L., Huang, C., Wang, J.-W., Pastorin, G. Investigations on Cellular Uptake Mechanisms and Immunogenicity Profile of Novel Bio-Hybrid Nanovesicles. Pharmaceutics, 2022, 14 (8), art. no. 1738.
Lee, C.K., Zhang, S., Venkatesan, G., Irsan, N., Chong, S.Y., Wang, J.-W., Goh, W.J., Panczyk, T., Tay, Y.Z., Hu, J., Ng, W.K., Wacker, M.G., Toh, W.S., Pastorin, G. Enhanced skin penetration of berberine from proniosome gel attenuates pain and inflammation in a mouse model of osteoarthritis. Biomaterials Science, 2022, 10 (7), pp. 1752-1764.
Venkatesan, G., Dancik, Y., Neupane, Y.R., Karkhanis, A.V., Bigliardi, P., Pastorin, G. Synthesis and Assessment of Non-allergenic Aromatic Amine Hair Dyes as Efficient Alternatives to Paraphenylenediamine. ACS Sustainable Chemistry and Engineering, 2022, 10 (2), pp. 838-849.
Venkatesan, G., Lim, Z.C., Karkhanis, A.V., Neupane, Y.R., Dancik, Y., Huang, C., Bigliardi, P., Pastorin, G. Investigations on detoxification mechanisms of novel para-phenylenediamine analogues through N-acetyltransferase 1 (NAT-1). Archives of Toxicology, 2022, 96 (1), pp. 153-165.
2021
Mast, M.-P., Modh, H., Champanhac, C., Wang, J.-W., Storm, G., Krämer, J., Mailänder, V., Pastorin, G., Wacker, M.G. Nanomedicine at the crossroads – A quick guide for IVIVC. Advanced Drug Delivery Reviews, 2021, 179, art. no. 113829.
Modh, H., Fang, D.J., Ou, Y.H., Yau, J.N.N., Kovshova, T., Nagpal, S., Knoll, J., Wallenwein, C.M., Maiti, K., Bhowmick, S., Gelperina, S., Pastorin, G., Wacker, M.G. Injectable drug delivery systems of doxorubicin revisited: In vitro-in vivo relationships using human clinical data. International Journal of Pharmaceutics, 2021, 608, art. no. 121073.
Ou, Y.-H., Liang, J., Czarny, B., Wacker, M.G., Yu, V., Wang, J.-W., Pastorin, G. Extracellular Vesicle (EV) biohybrid systems for cancer therapy: Recent advances and future perspectives. Seminars in Cancer Biology, 2021, 74, pp. 45-61.
Escudé Martinez de Castilla, P., Tong, L., Huang, C., Sofias, A.M., Pastorin, G., Chen, X., Storm, G., Schiffelers, R.M., Wang, J.-W. Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies. Advanced Drug Delivery Reviews, 2021, 175, art. no. 113801.
Neupane, Y.R., Huang, C., Wang, X., Chng, W.H., Venkatesan, G., Zharkova, O., Wacker, M.G., Czarny, B., Storm, G., Wang, J.-W., Pastorin, G. Lyophilization preserves the intrinsic cardioprotective activity of bioinspired cell-derived nanovesicles. Pharmaceutics, 2021, 13 (7), art. no. 1052.
Liu, C., Fang, Y., Zhang, X., Neupane, Y.R., Jiang, Z., Pastorin, G., Soh, S. Stimuli-responsive attachment for enabling the targeted release of carriers. Materials Chemistry Frontiers, 2021, 5 (11), pp. 4317-4326.
Goh, W.J., Tan, S.X., Pastorin, G., Ho, P.C.L., Hu, J., Lim, S.H. 3D printing of four-in-one oral polypill with multiple release profiles for personalized delivery of caffeine and vitamin B analogues. International Journal of Pharmaceutics, 2021, 598, art. no. 120360.
Ebadi, M., Bullo, S., Buskaran, K., Hussein, M.Z., Fakurazi, S., Pastorin, G. Dual‐functional iron oxide nanoparticles coated with polyvinyl alcohol/5‐fluorouracil/zinc‐aluminium‐layered double hydroxide for a simultaneous drug and target delivery system. Polymers, 2021, 13 (6), art. no. 855.
Ruman, U., Buskaran, K., Pastorin, G., Masarudin, M.J., Fakurazi, S., Hussein, M.Z. Synthesis and characterization of chitosan-based nanodelivery systems to enhance the anticancer effect of sorafenib drug in hepatocellular carcinoma and colorectal adenocarcinoma cells. Nanomaterials, 2021, 11 (2), art. no. 497, pp. 1-28.
Ebadi, M., Buskaran, K., Bullo, S., Hussein, M.Z., Fakurazi, S., Pastorin, G. Drug delivery system based on magnetic iron oxide nanoparticles coated with (polyvinyl alcohol-zinc/aluminium-layered double hydroxide-sorafenib). Alexandria Engineering Journal, 2021, 60 (1), pp. 733-747.
Venkatesan, G., Dancik, Y., Sinha, A., Kyaw, H.M., Srinivas, R., Dawson, T.L., Jr., Bigliardi, M., Bigliardi, P., Pastorin, G. Development of novel alternative hair dyes to hazardous para-phenylenediamine. Journal of Hazardous Materials, 2021, 402, art. no. 123712.
Tong, L., Hao, H., Zhang, Z., Lv, Y., Liang, X., Liu, Q., Liu, T., Gong, P., Zhang, L., Cao, F., Pastorin, G., Lee, C.N., Chen, X., Wang, J.-W., Yi, H. Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota. Theranostics, 2021, 11 (17), pp. 8570-8586.
Tram, N.D.T., Zhu, X., Ee, P.L.R., Pastorin, G. Carbon Nanomaterials for the Development of Biosensors for Microbe Detection and Diagnosis. RSC Nanoscience and Nanotechnology, 2021, 2021-January (48), pp. 293-330.
Ou, Y.-H., Zou, S., Goh, W.J., Wang, J.-W., Wacker, M., Czarny, B., Pastorin, G. Cell-Derived Nanovesicles as Exosome-Mimetics for Drug Delivery Purposes: Uses and Recommendations. Methods in Molecular Biology, 2021, 2211, pp. 147-170.
Huang, C., Neupane, Y.R., Lim, X.C., Shekhani, R., Czarny, B., Wacker, M.G., Pastorin, G., Wang, J.-W. Extracellular vesicles in cardiovascular disease. Advances in Clinical Chemistry, 2021, 103, pp. 47-95.
2020
Ebadi, M., Bullo, S., Buskara, K., Hussein, M.Z., Fakurazi, S., Pastorin, G. Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications. Scientific Reports, 2020, 10 (1), art. no. 21521.
Ebadi, M., Buskaran, K., Bullo, S., Hussein, M.Z., Fakurazi, S., Pastorin, G. Synthesis and cytotoxicity study of magnetite nanoparticles coated with polyethylene glycol and sorafenib–zinc/aluminium layered double hydroxide. Polymers, 2020, 12 (11), art. no. 2716, pp. 1-20.
Ou, Y.-H., Zou, S., Goh, W.J., Chong, S.Y., Venkatesan, G., Wacker, M.G., Storm, G., Wang, J.-W., Czarny, B., Pastorin, G., Woon, E.C.Y. Micro cell vesicle technology (mCVT): A novel hybrid system of gene delivery for hard-to-transfect (HTT) cells. Nanoscale, 2020, 12 (35), pp. 18022-18030.
2019
Lim, J., Koh, V.H.Q., Cho, S.S.L., Periaswamy, B., Choi, D.P.S., Vacca, M., De Sessions, P.F., Kudela, P., Lubitz, W., Pastorin, G., Alonso, S. Harnessing the Immunomodulatory Properties of Bacterial Ghosts to Boost the Anti-mycobacterial Protective Immunity Frontiers in Immunology, 2019, 10, art. no. 2737.
Venkatesan, G., Dancik, Y., Sinha, A., Bigliardi, M., Srinivas, R., Dawson, T., Valiyaveettil, S., Bigliardi, P., Pastorin, G. Facile synthesis of oligo anilines as permanent hair dyes: How chemical modifications impart colour and avoid toxicity. New Journal of Chemistry, 2019, 43 (41), pp. 16188-16199.
Maria V. Babak, Yang Zhi, Bertrand Czarny, Tan Boon Toh, Lissa Hooi, Edward Kai-Hua Chow, Wee Han Ang,* Dan Gibson* and Giorgia Pastorin*. Dual-targeting Dual-action Platinum(IV) Platform for Enhanced Anticancer Activity and Reduced Nephrotoxicity. Angew. Chemie Int. Ed., 2019, 58, 1-7.
Federico Stephanie; Margiotta, Enrico; Paoletta, Silvia; Kachler, Sonja; Klotz, Karl-Norbert; Jacobson, Kenneth; Pastorin, Giorgia; Moro, Stefano; Spalluto, Giampiero. Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines to develop functionalized ligands to target adenosine receptors: fluorescent ligands as an example. MedChemComm, 2019, 10, 1094 – 1108.
Siew lee Cheong*, Stephanie Federico, Giampiero Spalluto, Karl-Norbert Klotz, Giorgia Pastorin. The current status of multi-target drugs inpharmacotherapy for the treatment of Parkinson’s disease: transition from single-target to multi-target therapy. Drug Discovery today, 2019, S1359-6446(18)30036-9, doi: 10.1016/j.drudis.2019.05.003.
Kateryna Ohui, Maria V. Babak, Denisa Darvasiova, Alexander Roller, Daniel Vegh, Peter Rapta, Grace Rui Shi Guan, Yi Hsuan Ou, Giorgia Pastorin, and Vladimir B. Arion*. Redox-Active Organoruthenium(II)− and Organoosmium(II)− Copper(II) Complexes, with an Amidrazone−Morpholine Hybrid and [CuICl2]− as Counteranion and Their Antiproliferative Activity. Organometallics, 2019, 38(10), 2307-2318.
Suet Yen Chong, Choon Keong Lee, Chenyuan Huang, Yi Hsuan Ou, Christopher J. Charles, Arthur Mark Richards, Yub Raj Neupane, Maria Vazquez Pavon, Olga Zharkova, Giorgia Pastorin, Jiong-Wei Wang*. Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers. International Journal of Molecular Sciences, 2019, 20(13), pii: E3272.
Gopalakrishnan Venkatesan, Yuri Dancik, Arup Sinha, Mei Bigliardi, Ramasamy Srinivas, Thomas Dawson, Suresh Valivaveettil*, Paul Bigliardi*, Giorgia Pastorin*. Facile synthesis of oligo anilines as permanent hair dyes: How chemical modifications impart colour and avoid toxicity. New Journal of Chemistry, 2019, Accepted.
Aaron Tan, Maria V. Babak, Gopalakrishnan Venkatesan, Clarissa Lim, Karl-Norbert Klotz, Deron Raymond Herr, Siew Lee Cheong*, Stephanie Federico, Giampiero Spalluto, Wei-Yi Ong, Yu Zong Chen, Jason Siau Ee Loo* and Giorgia Pastorin*. Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy. Molecules, 2019, 24, 3661.
Ohui K, Afanasenko E, Bacher F, Ting RLX, Zafar A, Blanco-Cabra N, Torrents E, Dömötör O, May NV, Darvasiova D, Enyedy ÉA, Popović-Bijelić A, Reynisson J, Rapta P, Babak MV, Pastorin G, Arion VB*. New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. J Med Chem. 2019, 62, 512-530.
2018
Wei Jiang Goh, Shui Zou, Choon Keong Lee, Yi-Hsuan Ou, Jiong-Wei Wang, Bertrand Czarny and Giorgia Pastorin*. EXOPLEXs: Chimeric Drug Delivery Platform from the fusion of Cell Derived Nanovesicles and Liposomes. Biomacromolecules, 2018, 19(1), 22-30.
Chunyan Zhao, Jaymie Lin Siqi, Mahesh Choolani, Yock Young Dan, Giorgia Pastorin*, Han Kiat Ho*. Enhanced hepatic differentiation of human amniotic epithelial cells on polyethylene glycol linked multi-walled carbon nanotubes coated hydrogels. Journal of Tissue Engineering and Regenerative Medicine. 2018, 12(7), 1556-1566.
Yi-Ming Shao, Xiaohua Ma, Priyankar Paira, Aaron Tan, Deron Raymond Herr, Kah Leong Lim, Chee Hoe Ng, Gopalakrishnan Venkatesan, Karl-Norbert Klotz, Stephanie Federico, Giampiero Spalluto, Siew Lee Cheong, Yu Zong Chen* and Giorgia Pastorin*.
Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson’s disease treatment. PLoS One, 2018, 13(1), e0188212.
Jun Hu, Yuancai Dong, Wai Kiong Ng*, Giorgia Pastorin*, Reginald Beng Hee Tan. Preparation of drug nanocrystals embedded in mannitol microcrystals via liquid antisolvent precipitation followed by immediate (on-line) spray drying Advanced Powder Technology. Advanced Powder Technology, 2018, 29(4), 957-963.
Wei Jiang Goh, Shui Zou, Bertrand Czarny and Giorgia Pastorin*. nCVTs: a hybrid smart tumour targeting platform. Nanoscale, 2018, 10, 6812 – 6819.
Dean Ho, Kian Ping Loh, Gigi Ngar Chee Chiu, David Tai Wei Leong, Giorgia Pastorin, and Edward Kai-Hua Chow*. Clinical Applications of Carbon Nanomaterials in Diagnostics and Therapy. Advanced Materials, 2018, 30(47), e1802368.
Federico S, Margiotta E, Salmaso V, Pastorin G, Kachler S, Klotz KN, Moro S*, Spalluto G*. [1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A3 adenosine receptor subtype. Eur J Med Chem. 2018, 157, 837-851.
Mun Juinn Chow*, Maria V. Babak, Kwan Wei Tan, Mei Chi Cheong, Giorgia Pastorin, Christian GaiddonWee Han Ang*. Induction of the Endoplasmic Reticulum Stress Pathway by Highly Cytotoxic Organoruthenium Schiff-Base Complexes. Mol. Pharmaceutics 2018, 15(8), 3020-3031.
2017
Iris E. Allijn, Bertrand M.S. Czarny, Xiaoyuan Wang, Suet Y. Chong, Marek Weiler, Acarilia Eduardo da Silva, Josbert M. Metselaar, Giorgia Pastorin, Dominique P.V. de Kleijn, Gert Storm, Jiong-Wei Wang, Raymond M. Schiffelers. Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. Journal of Controlled Release, 2017, 247, 127-133.
Mun Juinn Chow*, Mohammad Alfiean, Giorgia Pastorin, Christian Gaiddon and Wee Han Ang*. Apoptosis-independent organoruthenium anticancer complexes that overcome multidrug resistance: self-assembly and phenotypic screening strategies Chem Sci. 2017, 8, 3641.
Dykas MM, Poddar K, Yoong SL, Viswanathan, Mathew S, Patra A, Saha S, Pastorin G, Venkatesan T*. Enhancing Image Contrast of Carbon Nanotubes on Cellular Background using Helium Ion Microscope by Varying Helium Ion Fluence. Journal of Microscopy, 2017, 269 (1), 14-22.
Tapas R. Nayak, Wang Hao, Aakansha Pant, Minrui Zheng, Hans Junginger, Wei Jiang Goh, Choon Keong Lee, Shui Zou, Sylvie Alonso, Bertrand Czarny, Gert Storm, Chorng Haur Sow, Chengkuo Lee * and Giorgia Pastorin*. ZnO nano-rod devices for intradermal delivery and immunization. Nanomaterials, 2017, 7, 147.
Wei Jiang Goh, Choon Keong Lee, Shui Zou, Esther Woon, Bertrand Czarny and Giorgia Pastorin*. Doxorubicin loaded Cell Derived Nanovesicles: An Alternative Targeted Approach for Anti-Tumor Therapy. International Journal of Nanomedicine, 2017, 12, 2759-2767.
Wei Jiang Goh, Zou Shui, Wei Yi Ong, Federico Torta, Alvarez Fernandez Alexandra, Raymond M. Schiffelers, Gert Storm, Jiong-Wei Wang, Bertrand Czarny* and Giorgia Pastorin*. Bioinspired Cell-Derived Nanovesicles versus Exosomes as Drug Delivery Systems: a Cost-Effective Alternative. Scientific Reports, 2017, 7, 14322.
Zhang C, Shao YM, Ma X, Cheong SL, Qin C, Tao L, Zhang P, Chen S, Zeng X, Liu H, Pastorin G*, Jiang Y*, Chen YZ*. Pharmacological relationships and ligand discovery of G protein-coupled receptors revealed by simultaneous ligand and receptor clustering. Journal of Molecular Graphics & Modeling. 2017, 76, 136-142.
2016
Panczyk, Tomasz; Konczak, Lukasz; Narkiewicz-Michalek, Jolanta; Pastorin, Giorgia. Corking and Uncorking Carbon Nanotubes By Metal Nanoparticles Bearing pH Cleavable Hydrazone Linkers. Theoretical Analysis Based On Molecular Dynamics Simulations. The Journal of Physical Chemistry Part C, 2016, 120(1), 639-649.
Siew Lee Cheong, Stephanie Federico, Aaron Boon Wu Tan, Giampiero Spalluto, Giorgia Pastorin. A3 Adenosine Receptor Ligands in the Treatment of Inflammation and Cancer. Pharmaceutical Formulation and Medicinal Chemistry: Mechanisms, Developments and Treatments. Bruce Moore Editor, 2015, Nova Publisher, New York.
Stephanie Federico, Antonella Ciancetta, Nicola Porta, Sara Redenti, Giorgia Pastorin, Barbara Cacciari, Karl Norbert Klotz, Stefano Moro, Giampiero Spalluto. 5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors. European Journal of Medicinal Chemistry 2016, 108, 529-541.
Hao Wang , Giorgia Pastorin , and Chengkuo Lee*. Toward Self-Powered Wearable Adhesive Skin Patch with Bendable Microneedle Array for Transdermal Drug Delivery. Adv. Sci. 2016, 3, 1500441.
Hao Wang, Zhuolin Xiang, Pastorin Giorgia, Xiaojing Mu, Ya Yang, Zhong Lin Wang, and Chengkuo Lee*. Triboelectric liquid volume sensor for self-powered lab-on-chip applications, Nano Energy, 2016, 23, 80-88.
Mun Juinn Chow, Cynthia Licona, Giorgia Pastorin, Georg Mellitzer, Wee Han Ang* and Christian Gaiddon*. Structural tuning of organoruthenium compounds allows oxidative switching to control ER stress pathways and bypass multidrug resistance. Chemical Science, 2016, 7, 4117-4124.
Sara Redenti, Antonella Ciancetta, Giorgia Pastorin, Barbara Cacciari, Stefano Moro, Giampiero Spalluto, Stephanie Federico. Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and Structurally Simplified Analogs. Chemistry and SAR Profile as Adenosine Receptor Antagonists. Current Topics in Medicinal Chemistry, 2016, 16 (128), 3224-3257.
Chow, Mun Juinn, Babak, Maria, Wong, Daniel Yuan Qiang, Pastorin, Giorgia, Gaiddon, Christian, Ang, Wee Han*. Structural Determinants of p53-Independence in Anticancer Ruthenium-Arene Schiff-base Complexes. Molecular Pharmaceutics, 2016, 13(7), 2543-2554.
Lukasz Konczak, Jolanta Narkiewicz-Michalek, Giorgia Pastorin, Tomasz Panczyk. Effects Of Intermolecular Interactions On The Stability Of Carbon Nanotube – Gold Nanoparticle Conjugates In Solution. International Journal of nanomedicine, 2016, 11, 5837-5849.
Tram Dai Thien Nhan, Wang Hao, Sugiarto Sigit, Li Tao, Ang Wee Han*, Lee Chengkuo*, Pastorin Giorgia*. Advances in nanomaterials and their applications in point of care (POC) devices for the diagnosis of infectious diseases. Biotechnology Advances, 2016, 34(8), 1275-1288.
2015
Jian Li, Sia Lee Yoong, Wei Jiang Goh, Bertrand Marcel Stanisl Czarny, Zhi Yang, Kingshuk Poddar, Michal Dykas, Abhijeet Patra, Thirumalai Venkatesan, Tomasz Panczyk, Chengkuo Lee*, Giorgia Pastorin*. In vitro Controlled Release of Cisplatin from Gold-Carbon Nanobottles via Cleavable Linkages. International Journal of Nanomedicine, 2015, 10, 7425–7441.
Chunyan Zhao, Henrik Andersen, Barbaros Ozyilmaz, Sundara Ramaprabhu, Giorgia Pastorin, Han Kiat Ho. Spontaneous and specific myogenic differentiation of human mesenchymal stem cells on polyethylene glycol-linked multi-walled carbon nanotube films for skeletal muscle engineering. Nanoscale, 2015, 7, 18239-18249.
Bi, Xinyan; Adriani, Giulia; Xu, Yang; Chakrabortty, Sabyasachi; Pastorin, Giorgia; Ho, Han Kiat; Ang, Wee Han; Chan, Yinthai. Gene Detection in Complex Biological Media using Semiconductor Nanorods within an Integrated Microfluidic Device. Analytical Chemistry, 2015, 87 (20), 10292–10298.
Sia Lee Yoong, Wei Liang Lau, Ang Yu Liu, D’Arcy Prendergast, Han Kiat Ho, Victor Chun Kong Yu, Chengkuo Lee, Wee Han Ang,* and Giorgia Pastorin*. Mitochondria-acting Hexokinase II Peptide Carried by Short-length Carbon Nanotubes with Increased Cellular Uptake, Endosomal Evasion, and Enhanced Bioactivity Against Cancer Cells. Nanoscale, 2015, 7, 13907 – 13917.
Zhuolin Xiang, Hao Wang, Giorgia Pastorin and Chengkuo Lee*. Development of A Flexible and Disposable Microneedle-Fluidic-System with Finger-Driven Drug Loading and Delivery Functions for Local Inflammation Treatment. JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2015, 24(3), 565-574.
Sergey Shityakov*, Ellaine Salvador, Giorgia Pastorin, Carola Förster. Blood–brain barrier transport studies, aggregation, and molecular dynamics simulation of multiwalled carbon nanotube functionalized with fluorescein isothiocyanate. International Journal of Nanomedicine, 2015, 10, 1703–1713.
Laura Muzi, Cécilia Ménard-Moyon, Julie Russier, Jian Li, Chee Fei Chin, Wee Han Ang, Giorgia Pastorin*, Gianfranco Risuleo, Alberto Bianco*. Diameter-dependent release of a cisplatin pro-drug from small and large functionalized carbon nanotubes. Nanoscale, 2015, 7(12), 5383-5394.
Chow, Mun Juinn; Licona, Cynthia; Wong, Daniel Yuan Qiang; Pastorin G, Gaiddon C., Ang Wee Han. Discovery and Investigation of Anticancer Ruthenium-Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly. Journal of Medicinal Chemistry, 2014, 57 (14), 6043-6059.
G. Venkatesan, P. Paira, S.L. Cheong, S. Federico*, K.N. Klotz, G. Spalluto*, G. Pastorin*. A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists. European Journal of Medicinal Chemistry, 2015, 92, 784-798.
Zhuolin Xiang, Hao Wang, Suresh Kanna Murugappan, Shih-Cheng Yen, Giorgia Pastorin* and Chengkuo Lee*. Dense vertical SU-8 microneedles drawn from a heated mold with precisely controlled volume. J. Micromech. Microeng. 2015, 25, 025013 (10 pp).
2014
Hao Wang, Zhuolin Xiang, Chih-Fan Hu, Giorgia Pastorin, Weileun Fang, and Chengkuo Lee. Microneedle Array Integrated with CNT Nanofilters for Controlled and Selective Drug Delivery. IEEE Journal of Microelectromechanical Systems. 2014, 23(5), 1036-1044. (October)
Siew Lee Cheong, Choon-Peng Chng*, Vamsi Krishna Kosaraju, Feng Xue, Stephanie Federico, Giampiero Spalluto, Chun Wei Yap and Giorgia Pastorin*. Modeling of antagonist binding site through a hA3 ‘hybrid’ homology model for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Journal of Computer-Aided Molecular Design. 2013, under revision.
Siew Lee Cheong, Choon-Peng Chng, Vamsi Krishna Kosaraju, Feng Xue, Stephanie Federico, Giampiero Spalluto, Chun Wei Yap,* and Giorgia Pastorin*. A new series of 2-Aryl-Pyrazolo-Triazolo-Pyrimidines as potent hA3 Adenosine Receptor Antagonists: QSAR analysis and CoMFA-guided Modeling of Antagonist Binding Site through a hA3 ‘hybrid’ Homology Model. European Journal of Medicinal Chemistry. Under revision.
Prachi Singh, Ganesh R. Kokil, Karnaker R. Tupally, Kingshuk Poddar, Aaron Tan, Venky venkatesan, Harendra Parekh* Giorgia Pastorin* Therapeutic Perspective in Type-1 Diabetes. 2015, Springer Briefs in Applied Sciences and Technology.
Stephanie Federico, Antonella Ciancetta, Nicola Porta, Sara Redenti, Giorgia Pastorin, Barbara Cacciari, Karl Norbert Klotz, Stefano Moro,* and Giampiero Spalluto*. Scaffold Decoration at Positions 5 and 8 of 1,2,4-Triazolo[1,5-c]Pyrimidines to Explore the Antagonist Profiling on Adenosine Receptors: A Preliminary SAR Study. Journal of Medicinal Chemistry, 2014, 57(14), 6210-6225.
Chee Fei Chin, Siew Qi Yap, Jian Li, Giorgia Pastorin* and Wee Han Ang*. Ratiometric Delivery of Cisplatin and Doxorubicin using Tumour-Targeting Carbon-Nanotubes Entrapping Platinum(IV) Prodrugs. Chemical Science, 2014, 5, 2265-2270.
Tomasz Panczyk*, Tatiana Da Ros, Giorgia Pastorin, Anna Jagusiak, Jolanta Narkiewicz-Michalek. Role of Intermolecular Interactions in Assemblies of Nanocontainers Composed of Carbon Nanotubes and Magnetic Nanoparticles. A Molecular Dynamics Study. The Journal of Physical chemistry, Part C, 2014, 118 (2), 1353–1363.
Jian Li , Aakansha Pant, Chee Fei Chin, Wee Han Ang*, Cécilia MENARD-MOYON, Tapas R. Nayak, Dan Gibson, Sundara Ramaprabhu, Tomasz Panczyk, Alberto BIANCO*, and Giorgia PASTORIN*. In vivo biodistribution of platinum-based drugs encapsulated into multi-walled carbon nanotubes. Nanomedicine, 2014, 10(7), 1465–1475.
Sia Lee Yoong, Bin Sheng Wong, Qi Lin Zhou, Chee Fei Chin, Jian Li, Thirumalai Venky Venkatesan, Han Kiat Ho, Victor Chun Kong Yu, Wee Han Ang*, Giorgia Pastorin*. Enhanced Cytotoxicity to Cancer Cells by Mitochondria-targeting MWCNTs Containing Platinum(IV) Prodrug of Cisplatin. Biomaterials, 2014, 35(2), 748–759.
2013
Chunyan Zhao, Aaron Tan, Giorgia Pastorin*, Han Kiat Ho*. Nanomaterial scaffolds for stem cell proliferation and differentiation in tissue engineering. Biotechnology Advances, 2013, 31(5), 654–668.
Hao Wang, Zhuolin Xiang, Chih-Fan Hu, Aakanksha Pant, Weileun Fang, Sylvie Alonso, Giorgia Pastorin* and Chengkuo Lee*. Development of Stretchable Membrane Based Nanofilters Using Patterned Array of Vertically Grown Carbon Nanotubes. Nanoscale, 2013, 5, 8488–8493
Bin Sheng WONG*, Sia Lee YOONG, Anna JAGUSIAK, Tomasz PANCZYK, Han Kiat HO, Wee Han ANG, Giorgia PASTORIN*. Carbon Nanotubes For Delivery of Small Molecule Drugs. Advanced Drug Delivery Reviews, 2013, 65, 1964-2015.
Panczyk, Tomasz; Jagusiak, Anna; Pastorin, Giorgia; Ang, Wee Han; Narkiewicz-Michalek, Jolanta. Molecular Dynamics Study of Cisplatin Release From Carbon Nanotubes Capped By Magnetic Nanoparticles. The Journal of Physical Chemistry. Part C: Energy Conversion and Storage, Optical and Electronic Devices, Interfaces, Nanomaterials, and Hard Matter. Section: C: Physical Processes in Nanomaterials and Nanostructures. 2013, 117 (33), 17327–17336.
Jan Gruber, Sheng Fong, Ce-Belle Chen, Sialee Yoong, Giorgia Pastorin, Sebastian Schaffer, Irwin Cheah, Barry Halliwell*. Mitochondria-targeted Antioxidants and Metabolic Modulators as Pharmacological Interventions to slow Ageing. Biotechnology Advances 2013, 31(5):563-92.
Siew Lee Cheong, Stephanie Federico, Gopalakrishnan Venkatesan, Alexander Laurence Mandel, Yi-Ming Shao, Stefano Moro, Giampiero Spalluto, Giorgia Pastorin*. Human A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry and in silico approaches. Medicinal Research Reviews, 2013, 33(2), 235-335.
Zhuolin Xiang, Wang Hao, Aakanksha Pant, Giorgia Pastorin*, Chengkuo Lee*. Development of vertical SU-8 microneedles for transdermal drug delivery by double drawing lithography technology. Biomicrofluidics, 2013, 7 (6), 6501.
Zhuolin Xiang, Wang Hao, Aakanksha Pant, Giorgia Pastorin*, Chengkuo Lee*. Development of Vertical SU-8 Microtubes Integrated with Dissolvable Tips for Transdermal Drug Delivery. Biomicrofluidics, 2013, 7, 026502.
Xiao Chen, Ce-Belle Chen, Chammika N. B. Udalagama, Minqin Ren, Kah Ee Fong, Lin Yue Lanry Yung, Pastorin Giorgia, Andrew Anthony Bettiol, Frank Watt. High-Resolution 3D Imaging and Quantification of Gold Nanoparticles in a Whole Cell Using Scanning Transmission Ion Microscopy. Biophysical Journal, 2013, 104, 1419-1425.
Jun Hu, Yuancai Dong, Giorgia Pastorin*, Wai Kiong Ng*, Reginald B. H. Tan. Spherical agglomerates of pure drug nanoparticles for improved pulmonary delivery in dry powder inhalers. Journal of Nanoparticle Research, 2013, 15, 1560.
Priyankar Paira, Chow Mun Juinn, Gopalakrishnan Venkatesan, Vamsi Krishna Kosaraju, Siew Lee Cheong, Karl-Norbert Klotz, Wee Han Ang*, Giorgia Pastorin*. Organoruthenium Antagonists of Human A3 Adenosine Receptors. Chemistry: a european journal, 2013, 19(25), 8321-8330.
Pastorin G. Carbon Nanotubes: From Bench Chemistry to Promising Biomedical Applications. Singapore: Pan Stanford publishing Pte Ltd.; 2010.
2012
Tapas R. Nayak and Giorgia Pastorin*. Nano-Carbon-Based Systems for the Delivery of Bioactive Agents: Pros and Cons. Chapter Nineteen. Nanopharmaceutics: The Potential Application of Nanomaterials. World Scientific publishing: August 2012. Pages: 535-569.
Jian Li, Siew Qi Yap, Sia Lee Yoong, Tapas Ranjan Nayak, Gary Wiratama Chandra, Wee Han Ang, Tomasz Panczyk, Sundara Ramaprabhu, Sandeep Kumar Vashist, Fwu-Shan Sheu, Aaron Tan, Giorgia Pastorin*. Carbon nanotube bottles for incorporation, release and enhanced cytotoxic effect of Cisplatin. Carbon, 2012, 50(4), 1625–1634.
Stephanie Federico, Antonella Ciancetta, Davide Sabbadin, Silvia Paoletta, Giorgia Pastorin, Barbara Cacciari, Karl Norbert Klotz, Stefano Moro and Giampiero Spalluto. Exploring the Directionality of 5-Substitutions in a New Series of 5-Alkylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine as a Strategy to Design Novel Human A3 Adenosine Receptor Antagonists. Journal of Medicinal Chemistry, 2012, 55, 9654−9668.
Tan A, Madani SY, Rajadas J, Pastorin G, Seifalian AM. Synergistic photothermal ablative effects of functionalizing carbon nanotubes with a POSS-PCU nanocomposite polymer. Journal of Nanobiotechnology. 2012,10(1), 34.
Wei Jiang Goh, Venkata S. Makam, Jun Hu, Lifeng Kang, Minrui Zheng, Sia Lee Yoong, Chammika N. B. Udalagama and Giorgia Pastorin*. Iron oxide filled magnetic carbon nanotube-enzyme conjugates for recycling of Amyloglucosidase: towards useful applications in biofuel production process. Langmuir, 2012, 28(49), 16864-16873.
Quan Tian, Winnie Wong, Yang Xu, Yinthai Chan, Han Kiat Ho, Giorgia Pastorin and Wee Han Ang*. Immobilisation of quantum dots by bio-orthogonal PCR amplification and labelling for direct gene detection and quantitation. Chem Commun 2012, 48, 5467-5469.
Jian Li, Siew Qi Yap, Chee Fei Chin, Quan Tian, Sia Lee Yoong, Giorgia Pastorin* and Wee Han Ang*.Platinum(IV) prodrugs entrapped within multiwalled carbon nanotubes: Selective release by chemical reduction and hydrophobicity reversal. Chemical Science, 2012, 3, 2083-2087.
Lara Lacerda, Julie Russier, Giorgia Pastorin, M. Antonia Herrero, Enrica Venturelli, Hélène Dumortier, Khuloud T. Al-Jamal, Maurizio Prato, Kostas Kostarelos*, Alberto Bianco*. Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes. Biomaterials, 2012, 33 (11), 3334–3343.
2011
Tomasz Panczyk, Philip J. Camp, Giorgia Pastorin and Tomasz P. Warzocha. Computational study of some aspects of chemical optimisation of a functional magnetically triggered nanocontainer. Journal of Physical Chemistry C, 2011, 115 (39), 19074–19083.
Siew Lee Cheong, Anton V. Dolzhenko, Silva Paoletta, Evelyn Pei Rong Lee, Sonja Kachler, Stephanie Federico, Karl-Norbert Klotz, Anna V. Dolzhenko, Giampiero Spalluto*, Stefano Moro* and Giorgia Pastorin*. Does the combination of optimal substitutions at the C2, N5 and N8 positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors? Bioorganic & Medicinal Chemistry, 2011, 19(20), 6120-6134.
Sandeep Kumar Vashist, Dan Zheng, Giorgia Pastorin, Khalid Al-Rubeaan, John H.T. Luong, Fwu-Shan Sheu*. Delivery of Drugs and Biomolecules using Carbon Nanotubes. Carbon, 2011, 49 (13), 4077-4097.
Aaron Tan, Lara Yildirimer, Jayakumar Rajadas, Hugo De La Peña, Giorgia Pastorin, Alexander Seifalian. Quantum dots and carbon nanotubes in oncology: a review on emerging theranostic applications in Nanomedicine. Nanomedicine, 2011, 6(6), 1101-1114.
Yupeng Ren*, Priyankar Paira, Tapas Ranjan Nayak, Wee Han Ang and Giorgia Pastorin*. Synthesis of Fullerene@Gold Core-Shell Nanostructure. Chemical Communications, 2011, 47 (27), 7710 – 7712.
Siew Lee Cheong*, Gopalakrishnan Venkatesan, Priyankar Paira, Ramasamy Jothibasu, Alexander Laurence Mandel, Stephanie Federico, Giampiero Spalluto,* and Giorgia Pastorin*. Pyrazolo derivatives as potent adenosine receptor antagonists: An overview on the structure-activity relationships. International Journal of Medicinal Chemistry, 2011, doi:10.1155/2011/480652.
Siew Lee Cheong, Stephanie Federico, Gopalakrishnan Venkatesan, Priyankar Paira, Yi-Ming Shao, Giampiero Spalluto, Chun Wei Yap*, Giorgia Pastorin*. Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorganic & Medicinal Chemistry Letters, 2011, 21, 2898-2905.
Sanyog Jain, Ijeoma F. Uchegbu, Guru Betageri, and Giorgia Pastorin. Nanotechnology in Advanced Drug Delivery. Journal of Drug Delivery, 2011, 2011, Article ID 343082, doi:10.1155/2011/343082.
Li Jian, Tapas Ranjan Nayak, Gary Wiratama Chandra, Venkata Sudheer Makam, Sia Lee Yoong, Sundara Ramaprabhu and Giorgia Pastorin*. Incorporation and delivery of bioactive molecules from smart carbon nano-devices. Asian Chemistry Letters, 2011, 16 (1), 1-8.
Tapas Ranjan Nayak, Henrik Andersen, Venkata Sudheer Makam, Clement Khaw, Sukang Bae, Xiangfan Xu, Pui-Lai Rachel Ee, Jong Hyun Ahn, Byung Hee Hong, Giorgia Pastorin*, Barbaros Özyilmaz*. Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells. ACS Nano, 2011, 5(6), 4670–4678.
Federico, S, S Paoletta, S L CHEONG, G PASTORIN, B Cacciari, S Stragliotto, K N Klotz, J Siegel, Z G Gao, K Jacobson, S Moro* and G Spalluto*. “Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines”. Journal of Medicinal Chemistry, 2011, 54 (3), pp 877–889.
2010
Tapas R. Nayak, Li Jian, Lee C. Phua, Han K. H o, Yupeng Ren and Giorgia Pastorin*. Thin films of functionalized Multiwalled carbon nanotubes as suitable scaffold materials for stem cells proliferation and bone formation. ACS Nano, 2010, 4(12), 7717-7725.
A.V. Dolzhenko, G.K. Tan, A.V. Dolzhenko, L.L. Koh and G. Pastorin. 8-Methyl-2-(4-trifluoromethylphenyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine methanol disolvate. Acta Crystallographica Section E, (2010), 66(7), o1835-o1836.
Anna V. Dolzhenko, Anton V. Dolzhenko, Geok Kheng Tan, Lip Lin Koh and Giorgia Pastorin. N’-Acetyl-5-amino-1-methyl-1H-pyrazole-4-carbohydrazonamide dihydrate. Acta Crystallographica Section E: Structure. Reports Online (2010). E66, o1209–o1210.
Siew Lee Cheong, Anna Dolzhenko, Silvia Paoletta, Stephanie Federico, Barbara Cacciari, Anton Dolzhenko, Sonja Kachler, Karl-Norbert Klotz, Stefano Moro, Giampiero Spalluto, Giorgia Pastorin*. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptor’s antagonists: New insights into Structure-affinity-relationship and Receptor-Antagonist Recognition. Journal of Medicinal Chemistry, 2010, 53(8), 3361-75.
Giorgia Pastorin, Stephanie Federico, Silvia Paoletta, Marta Corradino, Francesca Cateni, Barbara Cacciari, Karl-Norbert Klotz, Zhan-Guo Gao, Kenneth A. Jacobson, Giampiero Spalluto, Stefano Moro. Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand–receptor recognition process. Bioorganic & Medicinal Chemistry, 2010, 18, 2524-2536.
Giorgia Pastorin*, Tapas Ranjan Nayak and Yupeng Ren. Achievements and Challenges in the Delivery of bioactive molecules by Nano-Carbon-based Systems. International Journal of Biomedical Nanoscience and Nanotechnology (IJBNN), 2010, Vol. 1, Nos. 2/3/4, 267-289.
Anton Dolzhenko, Giorgia Pastorin, Anna Dolzhenko, Geok Kheng Tan and Lip Lin Koh. (4Z,6Z,12Z,14Z)- 2 , 1 0 – Dimethyl – 2, 8, 10, 16 – tetrahydrodipyrazolo [3, 4 – e: 3′, 4′ – l ][1,2,4,8,9,11]hexaazacyclotetradecine-4,12-diamine”. Acta Crystallographica Section E. Structure Reports Online, 65, no. 7 (2009): o1578-o1579. (Denmark). Publication no. 0412955.
2009
Anton Dolzhenko, Giorgia Pastorin, Anna Dolzhenko, Geok Kheng Tan and Lip Lin Koh. 4-Hydrazino-1-methylpyrazolo[3,4-d]pyrimidine”. Acta Crystallographica Section E: Structure. Reports Online, 65, no. 8 (2009): o1720-o1721. (Denmark). Publication no. 0414504.
Tapas R. Nayak, Pay Chin Leow, Pui-Lai Rachel Ee, Thevasahayam Arockiadoss, Sundara Ramaprabhu and Giorgia Pastorin*. Crucial Parameters responsible for Carbon Nanotubes toxicity. Current Nanoscience, 2010, 6(2), 141-154.
Anton V. Dolzhenko, Giorgia Pastorin, Anna V. Dolzhenko, Wai Keung Chui. A new synthesis of 2,8-disubstituted pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines. Tetrahedron Letters, 2009, 50, 5617-5621.
Wai-Keung Chui, Giorgia Pastorin, Aik-Jiang Lau. Learning the Use of Medicinal Herbs in Phytotherapy: A Tripartite Approach for Pharmacy Students. Pharmacy Education, 2009, 9 (1), 33-36.
Lisa Michielan, Chiara Bolcato, Stephanie Federico, Barbara Cacciari, Magdalena Bacilieri, Karl Norbet Klotz, Sonja Kachler, Giorgia Pastorin, Riccardo Cardin, Alessandro Sperduti, Giampiero Spalluto, and Stefano Moro. Combining Selectivity and Affinity Predictions using an Integrated Support Vector Machine (SVM) Approach: an Alternative Tool to Discriminate Between the Human Adenosine A2A and A3 Receptor Pyrazolo-Triazolo-Pyrimidine Antagonists Binding Sites. Bioorganic & Medicinal Chemistry, 2009, 17 (14), 5259-5274.
Cang-Rong Jason Teng and Giorgia Pastorin*. The Influence of Carbon Nanotubes on Enzyme Activity and Structure: Investigation of Different Immobilization Procedures through Enzyme Kinetics and Circular Dichroism Studies. Nanotechnology, 2009, 20, 255102.
Anton V. Dolzhenko, Giorgia Pastorin, Anna V. Dolzhenko, Wai Keung Chui. An aqueous medium synthesis and tautomerism study of 3(5)-amino-1,2,4-triazole. Tetrahedron Letters, 2009, 50 (18), 2124-2128.
Giorgia Pastorin*. Crucial Functionalizations of Carbon Nanotubes for an improved Drug Delivery: a valuable Option? Expert Opinion, Pharmaceutical Research, 2009, 26(4), 746-769.
2008
Nubia Yandar, Giorgia Pastorin, Maurizio Prato, Alberto Bianco, Manuel Elkin Patarroyo, Jose Manuel Lozano. Immunological profile of a Plasmodium vivax AMA-1 N-terminus peptide-carbon nanotube conjugate in an infected Plasmodium berghei mouse model. Vaccine, 2008, 26, 5864-5873.
Anton V. Dolzhenko, Giorgia Pastorin, Anna V. Dolzhenko, Wai Keung Chui. A convenient method for the synthesis of 7-aminosubstituted 1,2,4-triazolo[1,5-a][1,3,5]triazine-5-amines. Tetrahedron Letters, 2008, 49, 7180–7183.
Lara Lacerda, Hanene Ali-Boucetta, Maria A Herrero, Giorgia Pastorin, Alberto Bianco, Maurizio Prato, Kostas Kostarelos. Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes. Nanomedicine, 2008, 3(2), 149-161.
Bruno Fabre, Fanny Hauquier, Cyril Herrier, Giorgia Pastorin, Wei Wu, Alberto Bianco, Maurizio Prato, Philippe Hapiot, Dodzi Zigah, Mauro Prasciolu, Lisa Vaccari. Covalent Assembly and Micropatterning of Functionalized Multiwalled Carbon Nanotubes to Monolayer-Modified Si(111) Surfaces. Langmuir, 2008, 24, 6595-6602.
Chiara Bolcato, Claudia Cusan, Giorgia Pastorin, Giampiero Spalluto, Barbara Cacciari, Karl Norbert Klotz, Erika Morizzo, Stefano Moro. Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes. Purinergic Signalling, 2008, 4, 39–46.
Lisa Michielan, Magdalena Bacilieri, Andrea Schiesaro, Chiara Bolcato, Giorgia Pastorin, Giampiero Spalluto, Barbara Cacciari, Karl Norbet Klotz, Chosei Kaseda, Stefano Moro. Linear and Non-Linear 3D-QSAR Approaches in Tandem with Ligand-Based Homology Modeling as a Computational Strategy to Depict the Pyrazolo-Triazolo-Pyrimidine Antagonists Binding Site of the Human Adenosine A(2A) Receptor. Journal of chemical information and modeling, 2008, 48 (2), 350-363.
Yupeng Ren and Giorgia Pastorin*. Incorporation of Hexamethylmelamine inside Capped Carbon Nanotubes. Advanced Materials, 2008,20, 2031-2036.
Lara Lacerda, Anuradha Soundararajan, Ravi Singh, Giorgia Pastorin, Khuloud T. Al-Jamal, John Turton, Peter Frederik, Maria A. Herrero, Shouping Li, Ande Bao, Dimitris Emfietzoglou, Stephen Mather, William T. Phillips, Maurizio Prato, Alberto Bianco, Beth Goins, and Kostas Kostarelos. Dynamic Imaging of Functionalized Multi-Walled Carbon Nanotube Systemic Circulation and Urinary Excretion. Advanced Materials, 2008, 20, 225-230.
2007
Lara Lacerda, Giorgia Pastorin, David Gathercole, Joanna Buddle, Maurizio Prato Prato, Alberto Bianco, Kostas Kostarelos. Intracellular Trafficking of Carbon Nanotubes by Confocal Laser Scanning Microscopy. Advanced Materials, 2007, 19, 1480-1484.
Kostas Kostarelos, Lara Lacerda, Giorgia Pastorin, Wei Wu, Sebastien Wieckowski, Jacqueline Luangsivillay, Sylvie Godefroy, Davide Pantarotto, Jean-Paul Briand, Sylviane Muller, Maurizio Prato and Alberto Bianco. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nature Nanotechnology, 2007, 2, 108-113.
Alberto Bianco, Wei Wu, Giorgia Pastorin, Cédric Klumpp, Lara Lacerda, Charalambos D. Partidos, Kostas Kostarelos, Maurizio Prato. “Carbon nanotube-based vectors for delivering immunotherapeutics and drugs”, in Nanomaterials for Medical Diagnosis and Therapy, Kumar C. Ed., Wiley-VCH, Weinheim, 2007, pp. 85-142.
2006
Stefano Moro, Magdalena Bacilieri, Barbara Cacciari, Chiara Bolcato, Claudia Cusan, Giorgia Pastorin, Karl-Norbert Klotz and Giampiero Spalluto. The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: Application to a lead optimization of a human A3 adenosine receptor antagonist. Bioorganic & Medicinal Chemistry, 2006, 14, 4923–4932.
Lara Lacerda, Giorgia Pastorin, Wei Wu, Maurizio Prato, Alberto Bianco, Kostas Kostarelos. Luminescence of Functionalized Carbon Nanotubes as a Tool to Monitor Bundle Formation and Dissociation in Water: The Effect of Plasmid-DNA Complexation. Advanced Functional Materials, 2006, 16, 1839-1846.
Fanny Hauquier, Giorgia Pastorin, Philippe Hapiot, Maurizio Prato, Alberto Bianco, Bruno Fabre. Carbon nanotube-functionalized silicon surfaces with efficient redox communication. Chem. Commun. 2006, 43, 4536-4538.
Hélène Dumortier, Stéphanie Lacotte, Giorgia Pastorin, Riccardo Marega, Wei Wu, Davide Bonifazi, Jean-Paul Briand, Sylviane Muller, Maurizio Prato, Alberto Bianco. Functionalized carbon nanotubes are non toxic and preserve the functionality of primary immune cells. Nano Letters, 2006, 6(7), 1522-1528.
Giorgia Pastorin, Silvia Marchesan, Johan Hoebeke, Tatiana Da Ros, Laurence Ehret-Sabatier, Jean-Paul Briand, Maurizio Prato, Alberto Bianco. Design and Activity of Cationic Fullerene Derivatives as Inhibitors of Acetylcholinesterase. Organic & Biomelecular Chemistry (Advance article), 2006, 4, 2556-2562.
Ravi Singh, Davide Pantarotto, Lara Lacerda, Giorgia Pastorin, Cedric Klumpp, Maurizio Prato, Alberto Bianco and Kostas Kostarelos. Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. Proc Natl Acad Sci U S A. 2006, 103(9), 3357-3362.
Giorgia Pastorin, Tatiana Da Ros, Chiara Bolcato, Christian Montopoli, Stefano Moro, Barbara Cacciari, Pier Giovanni Baraldi, Katia Varani, Pier Andrea Borea and Giampiero Spalluto. Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations.J Med Chem. 2006, 49(5), 1720-1729.
Giorgia Pastorin, Wei Wu, Sébastien Wieckowski, Jean-Paul Briand, Kostas Kostarelos, Maurizio Prato and Alberto Bianco. Double functionalisation of carbon nanotubes for multimodal drug delivery. Chem. Commun. 2006, 21(11),1182-1184.
2005
Wei Wu, Sébastien Wieckowski, Giorgia Pastorin, Jean-Paul Briand, Maurizio Prato, Alberto Bianco. Targeted Delivery of Amphotericin B to Cells Using Functionalised Carbon Nanotubes. Angew. Chem. Int. Ed., 2005, 44, 6358-6362.
Giorgia Pastorin, Chiara Bolcato, Barbara Cacciari, Sonja Kachler, Karl Norbert Klotz, Christian Montopoli, Stefano Moro, Giampiero Spalluto. Synthesis, biological and modeling studies of 1,3-di-n-propyl-2,4-dioxo-6-methyl-8-(substituted)-1,2,3,4-tetrahydro [1,2,4] triazolo[3,4-f]purines as potential adenosine receptor antagonists. Il Farmaco, 2005, 60, 643-651.
Barbara Cacciari, Giorgia Pastorin, Chiara Bolcato, Giampiero Spalluto, Magdalena Bacilieri, Stefano Moro. A2B Adenosine Receptor Antagonists: Recent Developments. Mini Rev. Med. Chem., 2005, 12, 1053-1060.
Giorgia Pastorin, Kostas Kostarelos, Maurizio Prato, Alberto Bianco. Functionalized Carbon Nanotubes: Towards the Delivery of Therapeutic Molecules. Journal of Biomedical Nanotechnology, 2005, 1, 133-142.
Giorgia Pastorin, Chiara Bolcato, Barbara Cacciari, Sonja Kachler, Karl-Norbert Klotz, Christian Montopoli, Stefano Moro, Giampiero Spalluto. Synthesis, biological studies and molecular modeling investigation of 1,3-dimethyl-2,4-dioxio-6-methyl-8-(substituted)1,2,3,4- tetrahydro[1,2,4]triazolo[3,4-f]purines as potential adenosine receptor antagonists. Il Farmaco, 2005, 60, 299-306.
Barbara Cacciari, Giorgia Pastorin, Stefano Moro, Giampiero Spalluto. Potent and selective A2A adenosine receptor antagonists: Recent Improvements. Frontiers in Medicinal Chemistry, 2005, 2, 49-62.
Stefano Moro, Paolo Braiuca, Francesca Deflorian, Giorgia Pastorin, Cristina Ferrari, Barbara Cacciari, Pier Giovanni Baraldi, Katia Varani, Pier Andrea Borea, Giampiero Spalluto. Combined Target-based and Ligand-based Drug Design Approach as a Tool to Define a Novel 3D-Pharmacophore Model of Human A3 Adenosine Receptor Antagonists: Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine Derivatives as a Key Study. J. Med. Chem., 2005, 48, 152-162.
2003
Stefano Moro, Francesca Deflorian, Giampiero Spalluto, Giorgia Pastorin, Barbara Cacciari, Soo-Kyung Kim, Kenneth A. Jacobson. Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling. Chem. Commun., 2003, 2949-2956.
Giorgia Pastorin, Tatiana Da Ros, Giampiero Spalluto, Francesca Deflorian, Stefano Moro, Barbara Cacciari, Pier Giovanni Baraldi, Stefania Gessi, Katia Varani, Pier Andrea Borea. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A3 and A2B adenosine receptor subtypes: a molecular modeling investigation. J. Med. Chem., 2003, 46, 4287-4296.
Barbara Cacciari, Giorgia Pastorin, Giampiero Spalluto. Medicinal Chemistry of A2A adenosine receptor antagonists. Current Topic Med. Chem., 2003, 3, 403-411.
2002
Anna Maconi, Giorgia Pastorin, Tatiana Da Ros, Giampiero Spalluto, Zhan Guo Gao, Kenneth A. Jacobson, Pier Giovanni Baraldi, Barbara Cacciari, Katia Varani, Pier Andrea Borea. Synthesis, Biological properties and molecular modeling investigation of the first potent, selective and water soluble human A3 adenosine receptor antagonist. J. Med. Chem., 2002, 45, 3579-3582.
Pier Giovanni Baraldi, Barbara Cacciari, Romeo Romagnoli, Pier Andrea Borea, Katia Varani, Giorgia Pastorin, Tatiana Da Ros, Mojgan Aghazadeh Tabrizi, Francesca Fruttarolo, Giampiero Spalluto. Pyrazolo-triazolo-pyrimidine derivatives as adenosine receptor antagonists: A possible template for adenosine receptor subtypes? Current Pharmaceutical Design, 2002, 8, 2299-2332.
Pier Giovanni Baraldi, Barbara Cacciari, Stefano Moro, Giampiero Spalluto, Giorgia Pastorin, Tatiana Da Ros, Karl-Norbert Klotz, Katia Varani, Stefania Gessi, Pier Andrea Borea. Synthesis, biological activity and molecular modeling investigation of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A3 adenosine receptor antagonists. J. Med. Chem., 2002, 45, 770-780.
