Research Highlights

 

Please join us in congratulating Professor Ee and her team for their new online publication titled “Peptide nanonet trapping suppresses bacterial motility and delays antibiotic resistance emergence” published in Drug Resistance Updates (IF: 21.7).

 

About the research:

In the presence of antibiotics, motile bacteria can navigate chemical gradients for adaptation and survival. Antimicrobial peptides (AMPs) have been widely explored as adjuvant to improve the activity potency of antibiotics, but mainly through the disruption of bacterial membranes. In this work, the research team investigated the impact of nanonet trapping using fibrillating peptides, a mechanistically unique sub-group of AMPs, on motility recovery of bacteria and their capacity to develop antibiotic resistance.

Drug Resistance Updates publishes inspiring original research, commentary and expert reviews on important developments in drug resistance in infectious disease and cancer as well as novel drugs and strategies to overcome drug resistance. It covers both basic research and clinical aspects of drug resistance, and involves disciplines as diverse as molecular biology, biochemistry, cell biology, pharmacology, microbiology, preclinical therapeutics, oncology, and clinical medicine.

Congrats Rachel and Team!

 

https://doi.org/10.1016/j.drup.2025.101320