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Dr. ONG Pei Shi

BSc (Pharm) (Hons), National University of Singapore
PhD, National University of Singapore
Post Doctorate Fellowship, Weill Cornell Medical College and University of North Carolina at Chapel Hill, USA
Board Certified Pharmacotherapy Specialist (BCPS), Board of Pharmaceutical Specialties, USA

Department of Pharmacy, National University of Singapore
18 Science Drive 4, Singapore 117543
Tel: +65 6601 1236
Fax: +65 6779 1554
Email: phaops@nus.edu.sg

Teaching Activities in NUS

  • PR1103 Pharmacy Practice I (Lecturer)
  • PR2122 Biotechnology for Pharmacy (Lecturer)
  • PR5104 Pharmacy Practice III (Lecturer)
  • PR5113 Clinical Pharmacokinetics and Therapeutic Drug Monitoring (Module Coordinator and Lecturer)
  • PR5136 Pharm.D Seminar (Lecturer)
  • Pedagogical research article

Research Interests

Current treatment modalities remain to be optimized due to an insufficient understanding of disease etiology, variation in responses to existing therapeutic agents and drug-related problems from the use of concurrent drug therapies. It is thus my long term research goal to integrate my training in clinical pharmacy, molecular pharmacology and pharmacogenomics into a translational research platform that serves to optimize drug use through personalized medicine, medication therapy management and exploration of innovative drug regimens. In this regard, I’m interested in the following research areas:

 

Pharmacogenomics and clinical pharmacology

  • Identifying genetic variants that influence drug response and toxicity
  • Improving drug efficacy and safety of chemotherapeutic and psychoactive agents through therapeutic drug monitoring

 

Pharmacodynamics and molecular pharmacology

  • Understanding of molecular mechanisms of novel and investigational anticancer agents
  • Screening for effective combinations of anticancer drugs for both cancer treatment and metastasis reduction

 

Pharmacy practice research

  • Characterization of the efficacy and toxicity profiles of currently used medicines with an emphasis on oncology and neuropsychiatric medications
  • Understanding drug utilization through evaluating drug prescribing patterns in relation to current treatment guidelines and their influence on clinical outcomes

Professional activities

Invited peer reviewer for Clinical Cancer Research, Journal of Clinical Oncology, Annals of Oncology, Genes, Chromosomes and Cancer, etc